Radiochemistry Services at CMGI
- We produce a menu of PET radiotracers which are not commercially available
- We perform custom syntheses of novel PET radiotracers
- We produce isotopes and PET radiotracers on demand with our on-site cyclotron
- We can analyze metabolites in conjunction with PET imaging studies
CMGI Radiochemistry: A resource for PET Imaging
The Radiochemistry Facility is equipped for on-site production of radioisotopes and custom synthesis of radiotracers, to support PET imaging at UC Davis.
Cyclotron-produced PET isotopes
|F-18||110 minutes||Daily on demand|
|C-11||20 minutes||Daily on demand|
|N-13||10 minutes||Daily on demand|
Frequently used PET isotopes from third party suppliers
PET Radiotracers Available at CMGI
The PET radiotracers below are readily available at CMGI; new tracers can be added at client request.
Routine PET Radiotracers
PET Radiotracers for Oncology
PET Radiotracers for Neuroscience
|[11C]Raclopride||D2 Dopamine receptors|
|[11C]SCH23390||D1 Dopamine receptors|
|[11C]GR103545||Kappa opioid receptors|
|[11C]PK11195||TSPO targeting for neuroinflammation|
|[18F]PBR111||TSPO targeting for neuroinflammation|
|[18F]DPA-714||TSPIO targeting for neuroinflammation|
|[11C]PiB||Beta-amyloid plaques in neuronal tissue|
|[18F]UCB-H||Synaptic Vessel Glycoprotein 2A (SV2A)|
Miscellaneous/ Multiple Functionality
Method Development of New PET Radiotracers
- Suggestions for new PET radiotracers for prospective studies are always welcome. CMGI regularly adds new tracers to its menu, most at client request.
- CMGI can provide an estimate for development time and expense; method development may take as little as 3-6 weeks.
- CMGI pilot grant funding may help to develop tracers of general interest, subject to availability and approval.